iPROFILER
Tier 1 – Validated pre-screening markers
CCE 350 gene panel:
- based on the MSKCC-IMPACT panel
- hybridization capture-based next-generation sequencing assay for targeted deep sequencing of all exons and selected introns of 341 key cancer genes in formalin-fixed, paraffin embedded Tumours
- Utilises Roche-Kapa-Nimblegen hybridisation sequencing technology
Tier 2 – Exploratory pre-screening markers
- Nanostring
- cfDNA
- RNA seq
- WES
- Proteomics
Tier 2 – Companion diagnostics
- iPROFILERtissue can be used for validating potential companion diagnostics